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孙长凯

王朝百科·作者佚名  2010-06-19  
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孙长凯

孙长凯,男,汉族,1963年5月22日出生,大连市复县(今瓦房店市)人。神经病学主任医师、教授,神经生理学博士生导师、神经生物学博士后合作导师,大连医科大学脑疾病研究所所长,辽宁省脑疾病重点实验室暨辽宁省高校省级脑疾病研究重点实验室主任,大连医科大学辽宁省生理学重点学科带头人,美国Cleveland Clinic神经病学系癫癎中心客座教授,大连医科大学科技处长。从事医疗、科研、教学及其管理工作。主攻专业方向:脑保护与脑康复(脑卒中、癫癎、糖尿病脑病等重大脑疾病防治)的临床和基础研究。承担各类相关基金课题30余项,发表论文百余篇。

代表性论文(SCI/ISTP检索论文):

1.Sun CK, Huang YG, Wang DN,et al. An investigation of the GluRs-NOSs-RNI/ROIs cascade mechanism during the seizures induced by kainic acid in balb/c mice. Endothelium 1995,3:s119(Abstract)(第四届一氧化氮国际会议交流, ISTP收录,当年度SCI影响因子1.146)

2.Sun CK, Chong XQ, Huang YG. Spongiform encephalopathies in mainland China. Lancet 1996, 348:544 (Research Letter)(当年度SCI影响因子IF 17.948)

3. Chen JW,Sun CK, Huang YG. Nitric Oxide Synthase: Biochemistry and Molecular Biology. Prog Biochem Biophys 1996, 23 (3): 293-297(SCI影响因子IF 0.041)

4.Sun CK, Ju G, Huang YG. Implications of nitric oxide pathway in reactive gliosis within intractable seizure brain.Epilepsia1997,38(Suppl.3):189(第22届国际癫癎会议交流,当年度SCI影响因子IF 2.928)

5.Sun CK, Ju G, Huang YG. Expression of interleukin-6 in rat hippocampal formation during kainic acid induced seizures and the roles of nitric oxide pathway. Epilepsia1997,38 (Suppl.3): 231(第22届国际癫癎会议口头报告, ISTP收录,当年度SCI影响因子IF 2.928)

6.Sun CK, Ju G. Nitric oxide involved in epilepsy: Yes or no, what or why. Jpn J Pharmacol 1997,75(Suppl.1):89 (第五届一氧化氮国际会议交流, ISTP收录,SCI影响因子IF 1.210)

7. Wu LX,Sun CK (Corresponding Author), Fan M . Nogo and Nogo receptor . Prog Biochem Biophys 2002, 29 (6): 834-836(通讯作者,当年度SCI影响因子IF 0.160)

8. Kang XN,Sun CK (Corresponding Author), Fan M, Song ZJ, Zhao J, Wang JQ, Shi GX. Fourier transform infrared spectroscopic investigation of excitotoxicity-protective mechanism of monoclonal antibody against NMDAR. Prog Biochem Biophys 2003, 30 (2): 290-294(通讯作者,当年度SCI影响因子IF 0.048)

9. Kang XN,Sun CK (Corresponding Author), Fan M, Xue YN, Shao NS, Zhao J, Han DY, Shi GX. Screening of a NMDA receptor epitope from random phage display peptide library. Prog Biochem Biophys 2003, 30 (4): 599-604 (通讯作者,当年度SCI影响因子IF 0.048)

10.Zhan LB, Lu XG,Sun CK, Wang DP, Sui H, Jiang WZ, Wei W, Ma H. Antiexcitoxicity of Zi-Bu-Pi-Yin Recipe in vitro and Mechanisms. Acta Pharmacol Sin 2006; 27 (Suppl): 352 (XVth World Congress of Pharmoclogy, Beijing, ISTP收录,当年度SCI影响因子IF 1.397)

11.Du JL, An LJ,Sun CK, Men LL, Zhang XJ, Li CC. Overexpressing SelS may protect human umbilical vein endothelial cells from injuring by H2O2. Prog Biochem Biophys 2007, 34(4): 425-430(当年度SCI影响因子IF 0.214)

12.Wu LX,Sun CK (Corresponding Author),Zhang YM, Fan M, Xu J, Ma H, Zhang J. Involvement of the Snk-SPAR pathway in glutamate-induced excitotoxicity in cultured hippocampal neurons. Brain Res 2007;1168:38-45 (通讯作者,当年度SCI影响因子IF 2.218)

13.DU Jian-ling,Sun CK (Co-First Author), LÜ Bo, MEN Li-li, YAO Jun-jie, AN Li-jia and

SONG Gui-rong. Association of SelS mRNA expression in omental adipose tissue with Homa-IR and serum amyloid A in patients with type 2 diabetes mellitus. Chin Med J 2008; 121(13): 1165-1168(并列第一作者,上年度SCI影响因子IF 0.636)

14.Zhang L, Butler AJ,Sun CK, Sahgal V, Wittenberg GF, Yue GH. Fractal dimension assessment of brain white matter structural complexity post stroke in relation to upper-extremity motor function. Brain Res 2008; 1228: 229-240 (上年度SCI影响因子IF 2.218)

15. Liu S, Sun MZ,Sun CK, Zhao B, Greenaway FT, Zheng Q. A novel serine protease from the snake venom of Agkistrodon blomhoffii ussurensis. Toxicon. 2008; 52(7): 760-8 (上年度SCI影响因子IF 2.246)

16.Zhan LB, Sui H, Lu XG,Sun CK, Zhang J, Ma H. Effects of Zibu Piyin Recipe on SNK-SPAR Pathway in Neuron Injury Induced by Glutamate. Chin J Integr Med 2008 ,14(2):117-122 (SCI检索期刊)

17.Liang S, Yang F, Zhou C, Wang Y, Li S,Sun CK, Puglisi JL, Bers D, Sun C, Zheng J. Temperature-dependent activation of neurons by continuous near-infrared laser. Cell Biochem Biophys 2009; 53(1): 33-42 (2007 SCI影响因子IF 1.953)

18. Yang Q, Fang Y,Sun CK, Siemionow V, Ranganathan VK, Khoshknabi DS, Davis MP, Wash D, Sahgal V, Yue GH. Weakening of corticomuscular coupling during muscle fatigue. Brain Research, 2009 Jan 23; 1250: 101-12 (2007 SCI影响因子IF 2.218)

19. Xu LN, Han X, Qi Y, Xu YW, Yin LH, Peng JY, Liu KX,Sun CK(Corresponding Author). Multiple compounds determination and fingerprint analysis ofLidanpaishitablet and keli by high-performance liquid chromatography. Anal Chim Acta 2009 Feb 2;633(1):136-48 (通讯作者,2007 SCI影响因子IF 3.186)

20. Wang XF, Yang Q, Fan Z,Sun CK, Yue GH. Assessing time-dependent association between scalp EEG and muscle activation: a functional random-elects model approach. J Neurosci Methods 2009 Feb 15;177(1):232-40 (2007 SCI影响因子IF 1.884)

21. Yin LH, Lu BN, Qi Y, Xu LN, XuH, Xu YW, Peng JY,Sun CK(Corresponding Author). Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. J Pharm Biomed Anal 2009 May 1;49(4):1101-8 (通讯作者,2007 SCI影响因子IF 2.761)

22. Chen X,Sun CK(Co-First Author), Han GZ, Peng JY, Li Y, Liu YX, Lv YY, Liu KX, Zhou Q, Sun HJ. Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significanly correlated with cytochrome P450 suppression. World J Gastroenterol 2009 Apr 21;15(15):1829-35(并列第一作者,SCI检索期刊)

23. Sun W,Sun CK, Zhao H, Lin H, Han Q, Wang J, Ma H, Chen B, Xiao Z, Dai J. Improvement of sciatic nerve regeneration using laminin-binding human NGF-beta. PLoS One 2009 Jul 9;4(7):e6180 (2007PLoS Clinical TrialsSCI影响因子IF 4.774)

24. Sun W,Sun CK, Lin H, Zhao H, Wang J, Ma H, Chen B, Xiao Z, Dai J. The effect of collagen-binding NGF-beta on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model. Biomaterials 2009 Sep;30(27):4649-56. (2008 SCI影响因子IF 6.646)

 
 
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