厍学功
基本信息厍学功,男,兰州大学化学化工学院教授,博士生导师;中国科学院兰州化学物理研究所博士生导师。
兰州大学厍学功教授1966年7月12日生. 1999年7月毕业于兰州大学,获有机化学博士学位,师从著名有机化学家潘鑫复教授。
1999年08月---2001年07月,美国Colorado State University 从事博士后研究。合作导师,著名华人化学家史一安教授。
2001年07月---2002年10月,美国University of Oregon从事博士后研究。
2002年10月回国,于兰州大学任教。2004年入选中国科学院“百人计划”,2005年入选教育部“新世纪优秀人才支持计划”。国家基金委有机化学创新群体骨干成员。现任兰州大学有机化学第四研究所所长。在J.Am.Chem.Soc.,Angew.Chem.Int.Ed,J.Org.Chem.,Org.Lett.等国际著名学术期刊上发表论文四十余篇,曾获甘肃省科技进步二等奖两项,甘肃省高等学校科技进步一等奖两项,Thieme Chemistry Journals Award in 2007.
研究领域1.不对称催化反应
2.天然产物的不对称全合成及构效关系研究
主持课题现正在主持和完成国家自然科学基金、教育部科学技术研究重点项目、教育部高等学校博士点专项基金、甘肃省中青年科学基金、留学回国人员启动基金等多项课题。
代表性研究论文25. Efficient and Regioselective Synthesis of 5-Hydroxy-2-isoxazolines: Versatile Synthons for Isoxazoles, β-Lactams, and γ-Amino Alcohols
Shibing Tang, Jinmei He, Yongquan Sun, Liuer He, andXuegong She*
J. Org. Chem.2010, 75, 1961–1966
24. Pt-Catalyzed Tandem 1,2-Acyloxy Migration/Intramolecular[3+2] Cyclaoaddtion of Enynyl Esters
Huaiji Zheng, Jiyue Zheng, Binxun Yu, Qiang Chen, Xiaolei Wang, Yongping He Yangzhen andXuegong She*
J. Am. Chem. Soc.2010, 132 ,1788–1789.
23. An Efficient Method for Construction of the Angularly Fused 6,3,5-Tricyclic Skeleton of Mycorrhizin A and Its Analogues
Binxun Yu, Tuo Jiang, Weiguo Quan, Junpeng Li, Xinfu Pan andXuegong She*
Org. Lett.,2009, 11, 629–632
22. Total Synthesis of (−)-Bitungolide F
Yingpeng Su, Yanfen Xu, Junjie Han, Jiyue Zheng, Jing Qi, Tuo Jiang, Xinfu Pan andXuegong She*
J. Org. Chem.,2009, 74, 2743–2749
21. Asymmetric Total Synthesis and Revision of the Absolute Configuration of 4-Keto-Clonostachydiol
Junjie Han, Yingpeng Su, Tuo Jiang, Yanfen Xu, Xing Huo,Xuegong She* and Xinfu Pan
J. Org. Chem.,2009, 74, 3930–3932
20. Concise Total Synthesis of (+)-Aspergillide B
Jian Liu, Ke Xu, Jinmei He, Ling Zhang, Xinfu Pan andXuegong She*
J. Org. Chem.,2009, 74, 5063–5066
19. Efficient and Regioselective One-Pot Synthesis of 3-Substituted and 3,5-Disubstituted Isoxazoles
Shibing Tang, Jinmei He, Yongquan Sun, Liuer He andXuegong She*
Org. Lett.,2009, 11, 3982–3985
18. A Novel Prins Cyclization through Benzylic/Allylic C−H Activation
Binxun Yu, Tuo Jiang, Junpeng Li, Yingpeng Su, Xinfu Pan andXuegong She*
Org. Lett.,2009, 11, 3442–3445
17. Efficient Asymmetric Total Syntheses of Cryptocarya Triacetate, Cryptocaryolone, and Cryptocaryolone Diacetate
Xiaolei Wang, Wenkuan Wang, Huaiji Zheng, Yingpeng Su, Tuo Jiang, Yongping He andXuegong She*
Org. Lett.,2009, 11, 3136–3138
16. Application of a Domino Friedel-Crafts Acylation/Alkylation Reaction to the Formal Syntheses of(±) –Taiwaniaquinol B and (±) –Dichroanone
Shouchu Tang, Yanfen Xu, Jinmei He, Yongping He, Jiyue Zheng, Xinfu Pan, andXuegong She*
Org. Lett.,2008, 10, 1855-1858
15. The First Asymmetric Total Synthesis and Determination of Absolute Configuations of
Xestodecalactones B and C
Qiren Liang, Jiyong Zhang,Weiguo Quan, Yongquan Sun,Xuegong She*, and Xinfu Pan*
J. Org. Chem.,2007, 72, 2694-2697
14. First Total Syntheses and Spectral Data Corrections of 11- -Methoxycurvularin and 11-β-Methoxycurvularin
Qiren Liang, Yongquan Sun,Xuegong She*, and Xinfu Pan*.
J. Org. Chem.,2007, 72, 9846-9849
13. Total Synthesis of (+)-Machaeriol D with a key Regio-and Stereoselective S N 2’ Reaction
Qiaoling Wang, Qinggang Huang,Xuegong She*and Xinfu Pan*
Angew.Chem. Int. Ed.,2006,45, 3651-3653.
12. The N-Heterocyclic Carbene Catalyzed Nucleophilic Substitution Reaction for Construction of Benzopyrones and Benzofuranones
Jinmei He, Jiyue Zheng,Xuegong She*, Xinfu Pan
Org. Lett.,2006,8(20),4637-4640.
11. Concise Asymmetric Total Synthesis of Obolactone
Jiyong Zhang, Yang Li, Wenkuan Wang,Xuegong She*and Xinfu Pan*
J. Org. Chem.,2006,71, 2918-2921
10. Synthesis of 1,2,3,-trisubstituted cyclopropanes by MIRC reaction of dithianyllithiums with monocarboxylic vinyl epoxide analogues
Shouchu Tang, Xingang Xie, Xing Huo, Qiren Liang,Xuegong She*, Xinfu Pan
Tetrahedron Letters,2006,47(2), 205-208.
9. Efficient Synthesis of tribenzohexahydro[1,2]annulene and Itsderivatives in Ionic liquid
Yang Li, Jiyong Zhang, Wenkuan Wang, Qiang Miao,XuegongShe*and Xinfu Pan
J. Org. Chem.,2005,70(8), 3285.
8. Highly Diastereoseleoselective Formation of 1,2,3-Trisubtituted Cyclopropane Derivatives
Xingang Xie, Guoren Yue , Shouchu Tang, Xing Huo, Qiren Liang,XuegongShe*,Xinfu Pan*
Org. Lett.,2005,7(18), 4057-4059.
7. A Facile Approach to the Construction of 1H-Inden-1-one
Bo Chen, Xingang Xie, Jiangping Lu, Jiyong Zhang, Shouchu Tang,Xuegong She*, Xinfu Pan*
Synlett.,2006,2, 259-262.
6. Enantioselective total synthesis of aigialomycin D
Jiangping Lu, Xingang Xie, Bo Chen,Xuegong She*and Xinfu Pan
Tetrahedron:Asymmetry,2006,17,1066-1073.
5. Selective oxidation of benzylic or allylic hydroxyl group of sec-1,2-diol
Kun Peng, Fuxing Cheng,Xuegong She*,Chunhui Yang, Yuxin Cui, Xinfu Pan
Tetrahedron Letters,2005,46, 1217-1220.
4. An Enantioselectiv Synthesis of(S)-and ( R)-curcuphenol
Jiangping Lu, Xingang Xie, Bo Chen, Junjie Han,XuegongShe*,Xinfu Pan
Tetrahedron: Asymmetry,2005,16, 1435-1438.
3. Highly Enantioselective Epoxidation of α,β- unsaturated Ester by Chiral Dioxirane
Xin-Yan Wu,Xuegong She, Yian Shi
J. Am. Chem. Soc.,2002,124, 8792-8793
2. Designing New Chiral Ketone Catalysts. Asymmetric Epoxidation of cis and Terminal Olefins
Hongqi Tian,Xuegong She, Yian Shi
J. Org. Chem.,2002, 67, 2435-2446
1. Highly Enantioselective Epoxidation of cis-olefins by Chiral Dioxirane
Hongqi Tian,Xuegong She, Lianhe Shu, Hongwu Yu, and Yian Shi
J. Am. Chem. Soc.2000, 122,11551-11552