崔红娟
崔红娟,博士、教授,1988-2000年在西南大学完成本科、硕士、博士学习。2000-2001年,第四军医大学博士后,2001-2005年,俄亥俄医学院生化及肿瘤生物学助理研究员;2005-2009年,俄亥俄医学院生化及肿瘤生物学助理教授;2009-2010年,美国克利夫兰研究诊所干细胞生物学及再生医学助理教授;2010-2014 重庆市百人计划,2010-2014成为重庆市巴渝学者。首批重庆市“百名海外高层次人才集聚计划”入选者,也是西南大学引进的首位“百人计划”高层次创新人才,崔红娟博士到西南大学生物技术院蚕学重点实验室工作,从事细胞生物学特别是干细胞生物学领域科学研究及人才培养。
在美国期间,先后主持和参与了NIH、美国癌症协会和俄亥俄州多项课题的研究。在Nature Cel. Bio.,J.Biol.Chem.,Am.J.Pathol.,Molcancer Ther.等国际著名杂志发表高水平学术论文10余篇。
代表性论文:
1. Yang L,Hongjuan Cui, Wang Z, Zhang B, Ding J, Liu L, Ding HF. Loss of negative feedback control of nuclear factor-kappa B2 activity in lymphocytes leads to fatal lung inflammation.Am J pathol, 2010 Apr 2. Epib ahead of print.
2. Yang H, Zhu L, Ebraheim NA, Liu X, Castillo S, Tang T, Liu J,Hongjuan Cui.2009, Analysis of risk factors for recurrence after the resection of sacral chordoma combined with embolization.Spine J. Sep30.
3. Ling Mao, Yuan-Peng Xia, Yu-Nan Zhou, Ruo-Lian Dai, Xue Yang, Shu-Jie Duan, Xian Qiao, Yuan-Wu Mei, Bo Hu andHongjuan Cui, 2009 A critical role of Sonic Hedgehog signaling in maintaining the tumorigenicity of neuroblastoma cellsCancer Sci.Jun 26. [Epub ahead of print]
4. Goleeta Alam,Hongjuan Cui(co-principal author),Huilin Shi, Jane Ding, ling Mao, William A. Maltese, and Han-Fei Ding, MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development.Am J Pathol.2009 Aug; 175(2):856-66. Epub 2009 Jul 16.
5.Hongjuan Cui, Bo Hu, Tai Li, Jun Ma, Goleeta Alam, William T Gunning, and Han-Fei Ding, 2007. Bmi-1 is essential for the tumorigenicity of Neuroblastoma cells,American Journal of Pathology, 170 (4): 1370-1378.
6.Hongjuan Cui, Jun Ma, Jane Ding, Tai Li, Goleeta Alam, and Han-Fei Ding, 2006, Bmi-1 regulates differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner,Journal of Biological Chemistry, 281 (45): 34696-34704.
7.Hongjuan Cui, Tai Li, Han-Fei Ding, 2005, Linking of N-Myc to death receptor machinery in neuroblastoma cells,Journal of Biological Chemistry, 280: 9474-9481.
8. Yongqing Wang,Hongjuan Cui (Co-principal author), Allen Schroering, Jane L. Ding, William S. lane, Gaël McGill, David E. Fisher and Han-Fei Ding. 2002. NF-ĸB2 p100 is a pro-apoptotic protein with anti-oncogenic function.Nature Cell Biology. 4(11): 888-93.
9.Hongjuan Cui, Allen Schroering, and Han-Fei Ding. 2002. p53 mediated DNA damaging drug-induced apoptosis through a caspase-9-dependent pathway in Sh-SY5Y neuroblastoma cells.Molecular Cancer Therapeutics. 1: 679-686.