孙汭
孙汭教授，女，籍贯北京市，中国科技大学生命科学学院教授。1982毕业于山西医科大学（77级，本科），2000年获白求恩医科大学硕士学位（在职）。曾就职于山东省医学科学院基础医学研究所，任“山东省肿瘤免疫与医学基因工程重点实验室”常务副主任，1998年聘为研究员。1995.8--1996.8和 2001.3--2006.3先后在美国国立卫生研究院(NIH)癌症研究所（NCI）和酒精性疾病研究所（NIAAA）进行天然免疫学的合作研究。为主承担和完成了科研项目30余项。获得省部级科技进步奖6项。在中文核心期刊发表学术论文100余篇。发表SCI英文论文50余篇，其中在SCI英文论文中首位/通讯作者10余篇。1994年获第四届“中国青年科技奖”，1998年享受国务院政府特殊津贴，2005年获美国国立卫生研究院（NIH）杰出研究人员奖。
主要研究兴趣:
1. 肝脏的天然免疫耐受机理及其肝脏的免疫病理学研究；
2. 肝脏NK细胞对肝脏再生与损伤的负调机理；
3. 天然免疫受体“泛特异识别的结构生物学基础；
4．NK细胞功能相关基因工程蛋白质药物的研发
近五年代表性研究论文:
1. Sun R, Wei HM, Zhang JH, et al. Recombinant human prolactin improves antitumor effects of murine natural killer cells in vitro and in vivo. Neuroimmunomodulation; 2002; 10: 169-176.
2. Welniak LA, Sun R, Murphy WJ. The role of growth hormone in T-cell development and reconstitution. J Leukocyte Biol; 2002; 71: 381-387.
3. Sun R, Gault RA, Welniak LA, Tian ZG, Richards S and Murphy WJ. Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice. Biol Blood Marrow Transplant. 2003 Jul;9(7):426-434.
4. Sun R, Fan J, Wei HM, et al. Use of interleukin-15 for preparation of adherent NK cells from human peripheral blood: comparison with interleukin-2. J Immunol Methods. 2003;279: 79-90.
5. Sun R, Wei HM, Zhang JH, et al. The effects of natural killer-cell depletion on ex vivo expansion of hematopoietic progenitor cells from umbilical cord blood. Haematologica. 2003;88 : 561-569.
6. Sun R, Gao B. Negative regulation of liver regeneration by innate immunity (natural killer cells/interferon-gamma). Gastroenterology. 2004 Nov;127(5):1525-39.
7. Sun R, Tian Z, Kulkarni S, Gao B. IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD4+ T cell- and STAT3-dependent manners. J Immunol. 2004 May 1;172(9):5648-55.
8. Sun R, Li AL, Wei HM, et al. Expression of prolactin receptor and response to prolactin stimulation of human NK cell lines. Cell Res. 2004;14: 67-73
9. Radaeva S, Sun R, Pan HN, et al. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology., 2004; 39: 1332-1342
10. Sun R, Jaruga B, Kulkarni S, Sun HY and Gao B. IL-6modulates hepatocyte proliferation via inducytion of HCF/p21cip1: Regulation by SOCS3. Biochemical and Biophysical Research Communication. 2005; 338: 1943-1949
11. Sun R, Park O, Horiguchi N, Kulkarni S, Jeong W-IL, Sun HY, Radaeva S and Gao B. STAT1 contributes to dsRNA inhibition if liver regeneration after partial hepatectomy in mice. Hepatology. 2006; 44: 955-966.
12. Radaeva S, Sun S, Jaruga B, Nguyen VT, Tian Z, Gao B. Natural Killer Cells Ameliorate Liver Fibrosis by Killing Activated Stellate Cells in NKG2D- dependent and tumour necrosis factor-related apoptosis-inducing ligand-dependent manners. Ganstroenterology. 2006; 130: 435-452
13. Pan H, Sun R(co-first),, Jaruga B, Hong F, Kim WH, Gao B. Chronic Ethanol Consumption Inhibits Hepatic Natural Cytomegalovirus-Induced Hepatitis. Alcohol Clin Exp Res; 2006;30:1615-1623