李万程

李万程,湖南省“芙蓉学者”特聘教授,博导。1960年生于湖南衡山;1985年于湖南师大生物系获硕士学位;1992年9月获华盛顿大学动物学博士学位。
1992年进入美国哥伦比亚大学医学院从事博士后研究,先后在哥伦比亚大学,新泽西医科大学,明尼苏达大学任助理教授,目前在内布拉斯加大学任生物化学和分子生物学系以及眼科系副教授。
在《J. Cell. Biol》、《JBC》、《Oncogene》等杂志上发表论文40余篇。
2003年被湖南省教育厅批准为“芙蓉学者计划”首批特聘教授。
主要代表作:
1. Li, D. W-C., Liu Y, Liu J-P., P.C. Schmid., R. Schelosser, H. Feng, Y-M Xiao, W-B. Liu, Yan Q, Huang X-Q, H-G Chen, Gong L, Sun S-M, Deng M, and Yun Liu (2006). Protein Serine/Threonine Phosphatase-1 Dephosphorylates p53 at Ser-15 and Ser-37 to Modulate its Transcriptional and Apoptotic Activities. Oncogene. 25(21), 3006-3022.
2. Li, D. W-C., Liu, J-P., Mao Y. W., H. Xiang, J. Wang, W-Y Ma, Z. Dong, H. M. Pike, Rhoderick E. Brown and J. C., Reed (2005). Calcium-Activated RAF/MEK/ERK pathway mediates p53-dependent apoptosis and is abrogated by B-crystallin through Inhibition of Ras Activation. Mol. Biol. Cell. 16, 4437-4453.
3. Wang J, Feng H, Huang X-Q, Xiang H, Y-W. Mao, Liu J-P, Yan Q, Liu W-B, Liu Y, Deng M, Gong L, Sun S-M, Yun Liu and Li, D. W-C. (2005). hTERT immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway. J. Biol. Chem. 280, 22776-22787.
4. Huang X-Q, Wang J, Liu J-P, Feng H, Yan Q, Liu W-B, Liu Y, Sun S-M, Deng M, Gong L, Yun Liu and Li, D. W-C. (2005). hTERT extends proliferative lifespan and prevents replicative senescence and oxidative stress-induced apoptosis in human lens epithelial cells. Invest. Ophthalmol. Vis. Sci. 46, 5203-5213.
5. Feng, H., Xiang, H., Mao, Y-W., J. Wang, J-P., Liu, X-Q Huang, Y. Liu, S-J. Liu, C. Luo, X-J Zhang, Y. Liu, and Li, D. W-C. (2004). Human Bcl-2 activates RAF/MEK/ERK pathway and regulates AP-1 activity and downstream genes in rabbit Lens epithelial cells. Oncogene. 23, 7310-7321.
6. Mao, Y-W., Liu, J., Xiang, H., and Li, D. W-C. (2004). Human A and B-Crystallins Bind to Bax and Bcl-XS to sequester their translocation during staurosporine- induced apoptosis. Cell Death and Differ. 11, 512-526.